Philip Leopold

Professor Leopold focuses his research on gene therapy - viral mimics, host - virus interactions, and gene expression in human disease. He is an integral researcher in the field of Tissue Engineering, implementing the use of nanotechnology to revolutionize approaches for skin grafting, bone, nerve and cardiac cell regeneration.

Dr. Leopold Prof recently received funding to study "Rigid cationic carotenoid lipids as novel miRNA delivery vectors." In this role he will serve as Co-Principal on this project funded by the Qatar National Research Fund. The proposal will provide Prof. Leopold with $243,000 to support evaluation of new gene delivery vectors.

He has been awarded a patent for his invention “Crystal RG, Sato N, Leopold PL. Method of modulating hair growth. United States Patent #6,159,950”. He is a member of the New York Society of Experimental Microscopists, the Harvey Society, and the American Society for Gene Therapy, Education Committee Chair. Honors and awards have included the Georgetown University Biology Medal, Weill Medical College Excellence in Teaching Award, and Weill Medical College Charles L. Bardes Teaching Prize.

Research Images:
Selected Publications:
Pungente MD, Jubeli E, Øpstad C, Al-kawaz M, Barakat N, Ibrahim T, Khalique NA, Jones R, Leopold PL, Sliwka HR, Partali V.. (2012). Synthesis and preliminary investigations towards the siRNA delivery potential of novel, single-chain rigid cationic carotenoid lipids, Molecules, 17 3484-3500
Leopold PL, Vincent J, Wang H.. (2012). A comparison of epithelial-to-mesenchymal transition and re-epithelialization, Seminars in Cancer Biology, (in press)
Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG. (2009). Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing, Hum Gene Ther, 20 267-281
Leopold PL,* O’Mahony MJ,* Lian XJ,* Harvey BG, Crystal RG. (2009). Smoking is associated with shortened airway cilia, PLoS ONE, [* - these authors contributed equally to the work]. 4 (12), e8157
Berth SB, Leopold PL, Morfini G.. (2009). Virus-induced neuronal dysfunction and degeneration, Frontiers in Bioscience, 14 5239-5259
Contact Information:

Philip Leopold
pleopold@stevens.edu
Phone: 201.216.8957
515 McLean
Castle Point on Hudson
Hoboken NJ 07030

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